Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM274076'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274076 (US10071079, Example 862 | US10478424, Example 862) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)NCC2(C)COC2)CC1 Show InChI InChI=1S/C30H38N6O3/c1-19(2)27-23-11-21(20-7-9-35(10-8-20)14-26(37)31-15-30(3)16-39-17-30)5-6-24(23)34-28(27)22-12-25(38-4)29-32-18-33-36(29)13-22/h5-6,11-13,18-20,34H,7-10,14-17H2,1-4H3,(H,31,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274076 (US10071079, Example 862 | US10478424, Example 862) Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)NCC2(C)COC2)CC1 Show InChI InChI=1S/C30H38N6O3/c1-19(2)27-23-11-21(20-7-9-35(10-8-20)14-26(37)31-15-30(3)16-39-17-30)5-6-24(23)34-28(27)22-12-25(38-4)29-32-18-33-36(29)13-22/h5-6,11-13,18-20,34H,7-10,14-17H2,1-4H3,(H,31,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair