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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transcription factor AP-1' and Ligand = 'BDBM50092876'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor AP-1


(Homo sapiens (Human))
BDBM50092876
PNG
(2-Phenyl-pyrimidine-5-carboxylic acid (3,5-bis-tri...)
Show SMILES FC(F)(F)c1cc(NC(=O)c2cnc(nc2)-c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C19H11F6N3O/c20-18(21,22)13-6-14(19(23,24)25)8-15(7-13)28-17(29)12-9-26-16(27-10-12)11-4-2-1-3-5-11/h1-10H,(H,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells


J Med Chem 43: 3995-4004 (2000)


BindingDB Entry DOI: 10.7270/Q26M363N
More data for this
Ligand-Target Pair