BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily A member 1' and Ligand = 'BDBM50193601'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))		BDBM50193601
PNG
(CHEMBL3903533)
Show SMILES OC1(CCN(CC1)C(CNC(=O)C1(CC1)c1ccc(Cl)cc1)Cc1ccc(F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H27ClF4N2O2/c26-19-5-3-18(4-6-19)23(9-10-23)22(33)31-16-21(15-17-1-7-20(27)8-2-17)32-13-11-24(34,12-14-32)25(28,29)30/h1-8,21,34H,9-16H2,(H,31,33)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Temple University

Curated by ChEMBL


Assay Description
Inhibition of cinnamaldehyde-activated full length human TRPA1 channel expressed in 293T-Rex cells monitored at 5 sec interval by manual patch clamp ...

ACS Med Chem Lett 7: 658-9 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00245
BindingDB Entry DOI: 10.7270/Q2NS0WVD
More data for this
Ligand-Target Pair