Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM20458 (1-[(1R)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 7 | -46.5 | n/a | n/a | 5 | n/a | n/a | 7.4 | 25 |
Abbott Laboratories | Assay Description The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate... | J Pharmacol Exp Ther 323: 285-93 (2007) Article DOI: 10.1124/jpet.107.124305 BindingDB Entry DOI: 10.7270/Q28K77B0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM20458 (1-[(1R)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Displacement of [3H]A-778317 from human TRPV1 expressed in CHO cell membranes after 60 mins by scintillation counting method | J Med Chem 60: 8246-8252 (2017) Article DOI: 10.1021/acs.jmedchem.7b00859 BindingDB Entry DOI: 10.7270/Q2QV3PNP | |||||||||||
More data for this Ligand-Target Pair |