Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM210896 (US9273043, A125(e)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ... | US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM210896 (US9273043, A125(e)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 18.4 | n/a | n/a | n/a | n/a | n/a | 37 |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description Briefly, hTRPV1/CHO cells were cultured in growth media in a tissue culture dish at 37° C. in a CO2 incubator. On the day of the assay, culture m... | US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM210896 (US9273043, A125(e)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 23.9 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper... | US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G | |||||||||||
More data for this Ligand-Target Pair |