Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50254322'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254322 (CHEMBL467007 | N2-(2,6-dichlorophenyl)-N7-(6-(trif...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cn1 Show InChI InChI=1S/C17H9Cl2F3N6S/c18-9-2-1-3-10(19)12(9)27-16-28-13-14(24-7-25-15(13)29-16)26-8-4-5-11(23-6-8)17(20,21)22/h1-7H,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254322 (CHEMBL467007 | N2-(2,6-dichlorophenyl)-N7-(6-(trif...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cn1 Show InChI InChI=1S/C17H9Cl2F3N6S/c18-9-2-1-3-10(19)12(9)27-16-28-13-14(24-7-25-15(13)29-16)26-8-4-5-11(23-6-8)17(20,21)22/h1-7H,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair