Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50273021'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50273021 (1-(3-chloro-2-methylphenyl)-N-(3-oxo-3,4-dihydro-2...) Show SMILES Cc1c(Cl)cccc1N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C21H22ClN3O3/c1-13-16(22)3-2-4-18(13)25-9-7-14(8-10-25)21(27)23-15-5-6-19-17(11-15)24-20(26)12-28-19/h2-6,11,14H,7-10,12H2,1H3,(H,23,27)(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane				Bioorg Med Chem Lett 18: 4569-72 (2008) Article DOI: 10.1016/j.bmcl.2008.07.035 BindingDB Entry DOI: 10.7270/Q2154GV5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50273021 (1-(3-chloro-2-methylphenyl)-N-(3-oxo-3,4-dihydro-2...) Show SMILES Cc1c(Cl)cccc1N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C21H22ClN3O3/c1-13-16(22)3-2-4-18(13)25-9-7-14(8-10-25)21(27)23-15-5-6-19-17(11-15)24-20(26)12-28-19/h2-6,11,14H,7-10,12H2,1H3,(H,23,27)(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPR				Bioorg Med Chem Lett 18: 4569-72 (2008) Article DOI: 10.1016/j.bmcl.2008.07.035 BindingDB Entry DOI: 10.7270/Q2154GV5
					More data for this Ligand-Target Pair