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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50382243'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50382243
PNG
(CHEMBL2024492)
Show SMILES Oc1ccc2c(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cccc2c1
Show InChI InChI=1S/C18H12ClF3N2O2/c19-15-7-4-11(9-14(15)18(20,21)22)23-17(26)24-16-3-1-2-10-8-12(25)5-6-13(10)16/h1-9,25H,(H2,23,24,26)
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MMDB

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n/an/a 18n/an/an/an/an/an/a



Bayer Yakuhin, Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 expressed in CHOluc9aeq cells assessed as inhibition of capsaicin-stimulated response by aequorin and CRE-lucifear...

Bioorg Med Chem Lett 22: 3408-11 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.108
BindingDB Entry DOI: 10.7270/Q2C24XF7
More data for this
Ligand-Target Pair