Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50398533'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50398533 (CHEMBL2179148) Show SMILES CC(C(=O)NCc1ccc(nc1N1CCN(CC1)c1ccc(C)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C28H31F4N5O3S/c1-18-4-8-22(9-5-18)36-12-14-37(15-13-36)26-21(7-11-25(34-26)28(30,31)32)17-33-27(38)19(2)20-6-10-24(23(29)16-20)35-41(3,39)40/h4-11,16,19,35H,12-15,17H2,1-3H3,(H,33,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of capsaicin-induced activity by FLIPR assay				J Med Chem 55: 8392-408 (2012) Article DOI: 10.1021/jm300780p BindingDB Entry DOI: 10.7270/Q2TX3GH1
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50398533 (CHEMBL2179148) Show SMILES CC(C(=O)NCc1ccc(nc1N1CCN(CC1)c1ccc(C)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C28H31F4N5O3S/c1-18-4-8-22(9-5-18)36-12-14-37(15-13-36)26-21(7-11-25(34-26)28(30,31)32)17-33-27(38)19(2)20-6-10-24(23(29)16-20)35-41(3,39)40/h4-11,16,19,35H,12-15,17H2,1-3H3,(H,33,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38.3	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of pH-induced activity by FLIPR assay				J Med Chem 55: 8392-408 (2012) Article DOI: 10.1021/jm300780p BindingDB Entry DOI: 10.7270/Q2TX3GH1
					More data for this Ligand-Target Pair