Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50434924'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434924 (CHEMBL2385416) Show SMILES CC(C(=O)NCc1ccc(nc1OC1CCCC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C22H25F4N3O4S/c1-13(14-7-9-18(17(23)11-14)29-34(2,31)32)20(30)27-12-15-8-10-19(22(24,25)26)28-21(15)33-16-5-3-4-6-16/h7-11,13,16,29H,3-6,12H2,1-2H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay				Bioorg Med Chem 23: 6844-54 (2015) Article DOI: 10.1016/j.bmc.2015.10.001 BindingDB Entry DOI: 10.7270/Q2DZ0B4X
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434924 (CHEMBL2385416) Show SMILES CC(C(=O)NCc1ccc(nc1OC1CCCC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C22H25F4N3O4S/c1-13(14-7-9-18(17(23)11-14)29-34(2,31)32)20(30)27-12-15-8-10-19(22(24,25)26)28-21(15)33-16-5-3-4-6-16/h7-11,13,16,29H,3-6,12H2,1-2H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of capsaicin-induced activity by FLIPR assay				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434924 (CHEMBL2385416) Show SMILES CC(C(=O)NCc1ccc(nc1OC1CCCC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C22H25F4N3O4S/c1-13(14-7-9-18(17(23)11-14)29-34(2,31)32)20(30)27-12-15-8-10-19(22(24,25)26)28-21(15)33-16-5-3-4-6-16/h7-11,13,16,29H,3-6,12H2,1-2H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	6.0	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of pH 6 to 6.3-induced activity by FLIPR assay				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
					More data for this Ligand-Target Pair