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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 4' and Ligand = 'BDBM50195058'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 4


(Homo sapiens (Human))		BDBM50195058
PNG
(CHEMBL3979286)
Show SMILES Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)Nc2ccc(Cl)cc2)n1
Show InChI InChI=1S/C20H16ClN5OS2/c1-11-18(29-12(2)23-11)16-10-28-20(25-16)26-17-8-3-13(9-22-17)19(27)24-15-6-4-14(21)5-7-15/h3-10H,1-2H3,(H,24,27)(H,22,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.5n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...

Bioorg Med Chem Lett 26: 4930-4935 (2016)


Article DOI: 10.1016/j.bmcl.2016.09.013
BindingDB Entry DOI: 10.7270/Q2BC41H5
More data for this
Ligand-Target Pair