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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane protease serine 6' and Ligand = 'BDBM50032703'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 6


(Homo sapiens (Human))		BDBM50032703
PNG
(CHEMBL3354680)
Show SMILES N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1 |r|
Show InChI InChI=1S/C35H46N12O6S/c36-21(17-19-18-43-22-8-2-1-7-20(19)22)30(51)45-25(11-6-16-42-35(39)40)31(52)46-26(13-14-28(48)49)32(53)44-24(10-5-15-41-34(37)38)29(50)33-47-23-9-3-4-12-27(23)54-33/h1-4,7-9,12,18,21,24-26,43H,5-6,10-11,13-17,36H2,(H,44,53)(H,45,51)(H,46,52)(H,48,49)(H4,37,38,41)(H4,39,40,42)/t21-,24-,25-,26-/m0/s1
KEGG

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PC cid
PC sid
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Similars
Article
PubMed
 47n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Inhibition of human recombinant matriptase-2 using Boc-Gln-Ala-Arg-AMC as substrate by microplate reader analysis

J Med Chem 57: 10198-204 (2014)


Article DOI: 10.1021/jm5015633
BindingDB Entry DOI: 10.7270/Q2DJ5H73
More data for this
Ligand-Target Pair