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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane protease serine 6' and Ligand = 'BDBM50236921'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 6


(Homo sapiens (Human))		BDBM50236921
PNG
(CHEMBL4062334)
Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1 |r|
Show InChI InChI=1S/C37H42N10O6S/c38-26(16-21-7-11-24(48)12-8-21)33(51)45-29(17-22-9-13-25(49)14-10-22)34(52)46-30(18-23-19-41-20-43-23)35(53)44-28(5-3-15-42-37(39)40)32(50)36-47-27-4-1-2-6-31(27)54-36/h1-2,4,6-14,19-20,26,28-30,48-49H,3,5,15-18,38H2,(H,41,43)(H,44,53)(H,45,51)(H,46,52)(H4,39,40,42)/t26-,28-,29-,30-/m0/s1
KEGG

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PC cid
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Similars
Article
PubMed
 56n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...

Eur J Med Chem 129: 110-123 (2017)


Article DOI: 10.1016/j.ejmech.2017.02.006
BindingDB Entry DOI: 10.7270/Q2GB269P
More data for this
Ligand-Target Pair