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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane protease serine 6' and Ligand = 'BDBM50236922'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 6


(Homo sapiens (Human))		BDBM50236922
PNG
(CHEMBL4089262)
Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)c(O)c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1 |r|
Show InChI InChI=1S/C40H44N8O8S/c41-27(18-22-7-12-25(49)13-8-22)36(54)46-30(19-23-9-14-26(50)15-10-23)38(56)47-31(20-24-11-16-32(51)33(52)21-24)37(55)45-29(5-3-17-44-40(42)43)35(53)39-48-28-4-1-2-6-34(28)57-39/h1-2,4,6-16,21,27,29-31,49-52H,3,5,17-20,41H2,(H,45,55)(H,46,54)(H,47,56)(H4,42,43,44)/t27-,29-,30-,31-/m0/s1
KEGG

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Similars
Article
PubMed
 5n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...

Eur J Med Chem 129: 110-123 (2017)


Article DOI: 10.1016/j.ejmech.2017.02.006
BindingDB Entry DOI: 10.7270/Q2GB269P
More data for this
Ligand-Target Pair