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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane protease serine 6' and Ligand = 'BDBM50236927'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 6


(Homo sapiens (Human))		BDBM50236927
PNG
(CHEMBL4065870)
Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1 |r|
Show InChI InChI=1S/C44H46N8O6S/c45-33(23-26-12-17-31(53)18-13-26)40(56)50-36(24-27-14-19-32(54)20-15-27)42(58)51-37(25-28-11-16-29-6-1-2-7-30(29)22-28)41(57)49-35(9-5-21-48-44(46)47)39(55)43-52-34-8-3-4-10-38(34)59-43/h1-4,6-8,10-20,22,33,35-37,53-54H,5,9,21,23-25,45H2,(H,49,57)(H,50,56)(H,51,58)(H4,46,47,48)/t33-,35-,36-,37-/m0/s1
KEGG

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PC sid
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Similars
Article
PubMed
 5.30n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...

Eur J Med Chem 129: 110-123 (2017)


Article DOI: 10.1016/j.ejmech.2017.02.006
BindingDB Entry DOI: 10.7270/Q2GB269P
More data for this
Ligand-Target Pair