Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transthyretin' and Ligand = 'BDBM249534'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transthyretin (Homo sapiens (Human))	BDBM249534 (US10072016, Compound 132 | US10407433, Compound 13...) Show SMILES Fc1cc(F)c(c(c1)C1CCN(CC1)C(=O)c1nnc2ccc(cn12)C#N)C(F)(F)F Show InChI InChI=1S/C20H14F5N5O/c21-13-7-14(17(15(22)8-13)20(23,24)25)12-3-5-29(6-4-12)19(31)18-28-27-16-2-1-11(9-26)10-30(16)18/h1-2,7-8,10,12H,3-6H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.5	n/a	n/a	n/a	n/a	7.4	25
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK US Patent					Assay Description Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...				US Patent US10072016 (2018) BindingDB Entry DOI: 10.7270/Q2QJ7KBT
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