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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Triacylglycerol Hydrolase' and Ligand = 'BDBM23051'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Triacylglycerol Hydrolase


(Homo sapiens (Human))
BDBM23051
PNG
(7-(4-nitrophenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-2...)
Show SMILES [O-][N+](=O)c1ccc(CCCCCCC(=O)c2ncc(o2)-c2ccccn2)cc1
Show InChI InChI=1S/C21H21N3O4/c25-19(21-23-15-20(28-21)18-8-5-6-14-22-18)9-4-2-1-3-7-16-10-12-17(13-11-16)24(26)27/h5-6,8,10-15H,1-4,7,9H2
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 5.00E+4n/an/an/an/an/a25



The Scripps Research Institute



Assay Description
Inhibition of TGH activity was assayed using COS-7 expressed TGH and the chromogenic substrate. IC50 values were determined from the inhibition obser...


J Med Chem 50: 3359-68 (2007)


Article DOI: 10.1021/jm061414r
BindingDB Entry DOI: 10.7270/Q2DR2SSH
More data for this
Ligand-Target Pair