Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM311863'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM311863 (US10155972, Compound Incyte 1) Show SMILES Nc1nonc1\C(Nc1cc(F)cc(Cl)c1)=N/O Show InChI InChI=1S/C9H7ClFN5O2/c10-4-1-5(11)3-6(2-4)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
Iomet Pharma Ltd. US Patent					Assay Description In two separate assays, 0.045 μg/μl of human IDO protein was pre-incubated for 10 min at RT with test compounds NewLink 1 and Incyte 1 in t...				US Patent US10155972 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RDS
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM311863 (US10155972, Compound Incyte 1) Show SMILES Nc1nonc1\C(Nc1cc(F)cc(Cl)c1)=N/O Show InChI InChI=1S/C9H7ClFN5O2/c10-4-1-5(11)3-6(2-4)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Iomet Pharma Ltd. US Patent					Assay Description In two separate assays, 2.5 μg/μl of human TDO protein was pre-incubated for 10 minutes at RT with test compounds 680C91 and LM10 in the pr...				US Patent US10155972 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RDS
					More data for this Ligand-Target Pair