Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tryptophan 2,3-dioxygenase (Homo sapiens (Human)) | BDBM339955 (N1-(5-(6-fluoro-1H-indol-3- yl)pyridin-2-yl)-N2,N2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
iTeos Therapeutics US Patent | Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me... | US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9 | |||||||||||
More data for this Ligand-Target Pair |