BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 1' and Ligand = 'BDBM50243020'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50243020 ((S)-2-amino-3-(4-(4-amino-6-((R)-1-(naphthalen-2-y...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of human recombinant TPH1 by continuous fluorescence assay				Bioorg Med Chem Lett 19: 5229-32 (2009) Article DOI: 10.1016/j.bmcl.2009.07.005 BindingDB Entry DOI: 10.7270/Q2MS3SV0
Princ Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50243020 ((S)-2-amino-3-(4-(4-amino-6-((R)-1-(naphthalen-2-y...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				J Med Chem 51: 3684-7 (2008) Article DOI: 10.1021/jm800338j BindingDB Entry DOI: 10.7270/Q2PK0FZM
Princ Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)