Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM50243618 ((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of TPH1 (unknown origin) | J Med Chem 51: 3684-7 (2008) Article DOI: 10.1021/jm800338j BindingDB Entry DOI: 10.7270/Q2PK0FZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 1 (Rattus norvegicus) | BDBM50243618 ((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 48 | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesis | J Med Chem 51: 3684-7 (2008) Article DOI: 10.1021/jm800338j BindingDB Entry DOI: 10.7270/Q2PK0FZM | |||||||||||
More data for this Ligand-Target Pair |