Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'Tyrosinase' and Ligand = 'BDBM50205806'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Homo sapiens (Human))	BDBM50205806 (CHEMBL3969839) Show SMILES Oc1cc2O\C(=C/c3ccc(=O)n(O)c3)C(=O)c2c(O)c1 Show InChI InChI=1S/C14H9NO6/c16-8-4-9(17)13-10(5-8)21-11(14(13)19)3-7-1-2-12(18)15(20)6-7/h1-6,16-17,20H/b11-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50205806 (CHEMBL3969839) Show SMILES Oc1cc2O\C(=C/c3ccc(=O)n(O)c3)C(=O)c2c(O)c1 Show InChI InChI=1S/C14H9NO6/c16-8-4-9(17)13-10(5-8)21-11(14(13)19)3-7-1-2-12(18)15(20)6-7/h1-6,16-17,20H/b11-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50205806 (CHEMBL3969839) Show SMILES Oc1cc2O\C(=C/c3ccc(=O)n(O)c3)C(=O)c2c(O)c1 Show InChI InChI=1S/C14H9NO6/c16-8-4-9(17)13-10(5-8)21-11(14(13)19)3-7-1-2-12(18)15(20)6-7/h1-6,16-17,20H/b11-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Grenoble-Alpes/CNRS Curated by ChEMBL					Assay Description Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...				ACS Med Chem Lett 8: 55-60 (2017) Article DOI: 10.1021/acsmedchemlett.6b00369 BindingDB Entry DOI: 10.7270/Q24F1SQN
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50205806 (CHEMBL3969839) Show SMILES Oc1cc2O\C(=C/c3ccc(=O)n(O)c3)C(=O)c2c(O)c1 Show InChI InChI=1S/C14H9NO6/c16-8-4-9(17)13-10(5-8)21-11(14(13)19)3-7-1-2-12(18)15(20)6-7/h1-6,16-17,20H/b11-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by spectrophotometric analysis				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50205806 (CHEMBL3969839) Show SMILES Oc1cc2O\C(=C/c3ccc(=O)n(O)c3)C(=O)c2c(O)c1 Show InChI InChI=1S/C14H9NO6/c16-8-4-9(17)13-10(5-8)21-11(14(13)19)3-7-1-2-12(18)15(20)6-7/h1-6,16-17,20H/b11-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by spectrophotometric analysis				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50205806 (CHEMBL3969839) Show SMILES Oc1cc2O\C(=C/c3ccc(=O)n(O)c3)C(=O)c2c(O)c1 Show InChI InChI=1S/C14H9NO6/c16-8-4-9(17)13-10(5-8)21-11(14(13)19)3-7-1-2-12(18)15(20)6-7/h1-6,16-17,20H/b11-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Grenoble-Alpes/CNRS Curated by ChEMBL					Assay Description Inhibition of tyrosinase in human MNT1 cell lysate pretreated prior to addition of L-DOPA as substrate measured after 3 hrs				ACS Med Chem Lett 8: 55-60 (2017) Article DOI: 10.1021/acsmedchemlett.6b00369 BindingDB Entry DOI: 10.7270/Q24F1SQN
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50205806 (CHEMBL3969839) Show SMILES Oc1cc2O\C(=C/c3ccc(=O)n(O)c3)C(=O)c2c(O)c1 Show InChI InChI=1S/C14H9NO6/c16-8-4-9(17)13-10(5-8)21-11(14(13)19)3-7-1-2-12(18)15(20)6-7/h1-6,16-17,20H/b11-3-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+5	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Grenoble-Alpes/CNRS Curated by ChEMBL					Assay Description Inhibition of tyrosinase in human MNT1 cells assessed as suppression of melanin biosynthesis measured after 96 hrs				ACS Med Chem Lett 8: 55-60 (2017) Article DOI: 10.1021/acsmedchemlett.6b00369 BindingDB Entry DOI: 10.7270/Q24F1SQN
					More data for this Ligand-Target Pair