new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine kinase receptor A (TrkA)' and Ligand = 'BDBM226529'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226529
PNG
(US9328096, 222)
Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(ccc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)ccn1
Show InChI InChI=1S/C28H21ClFN7O2/c29-21-9-8-18(26-22(30)7-4-11-33-26)14-20(21)27(38)35-25-15-23(36-37(25)19-5-2-1-3-6-19)28(39)34-16-17-10-12-32-24(31)13-17/h1-15H,16H2,(H2,31,32)(H,34,39)(H,35,38)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.37n/an/an/an/an/a37



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


US Patent US9328096 (2016)


BindingDB Entry DOI: 10.7270/Q2FN152J
More data for this
Ligand-Target Pair