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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine kinase receptor A (TrkA)' and Ligand = 'BDBM226856'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226856
PNG
(US9328096, 549)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCC2CCOC2)c(Cl)cc1Cl
Show InChI InChI=1/C27H22Cl2FN5O3/c28-20-12-21(29)19(11-18(20)25-22(30)7-4-9-31-25)26(36)33-24-13-23(27(37)32-14-16-8-10-38-15-16)34-35(24)17-5-2-1-3-6-17/h1-7,9,11-13,16H,8,10,14-15H2,(H,32,37)(H,33,36)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.66n/an/an/an/an/a37



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


US Patent US9328096 (2016)


BindingDB Entry DOI: 10.7270/Q2FN152J
More data for this
Ligand-Target Pair