new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine kinase receptor A (TrkA)' and Ligand = 'BDBM226992'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226992
PNG
(US9328096, 680)
Show SMILES Cc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)c(N)n1
Show InChI InChI=1S/C29H23ClFN7O2/c1-17-10-11-18(27(32)35-17)16-34-29(40)25-15-26(38(37-25)19-7-3-2-4-8-19)36-28(39)20-13-21(23(31)14-22(20)30)24-9-5-6-12-33-24/h2-15H,16H2,1H3,(H2,32,35)(H,34,40)(H,36,39)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.65n/an/an/an/an/a37



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


US Patent US9328096 (2016)


BindingDB Entry DOI: 10.7270/Q2FN152J
More data for this
Ligand-Target Pair