BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM50322548'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))		BDBM50322548
PNG
(CHEMBL1169705 | N-{4-[(Hexahydro-4-methyl-1H-1,4-d...)
Show SMILES CN1CCCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4ccccn34)cc2C(F)(F)F)CC1
Show InChI InChI=1S/C31H30F3N5O/c1-22-7-8-24(18-23(22)10-12-27-20-35-29-6-3-4-15-39(27)29)30(40)36-26-11-9-25(28(19-26)31(32,33)34)21-38-14-5-13-37(2)16-17-38/h3-4,6-9,11,15,18-20H,5,13-14,16-17,21H2,1-2H3,(H,36,40)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of wild type human ABL after 1 hr by TR-FRET assay

J Med Chem 53: 4701-19 (2010)


Article DOI: 10.1021/jm100395q
BindingDB Entry DOI: 10.7270/Q27P8ZKX
More data for this
Ligand-Target Pair