Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM143326'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM143326 (US8940893, 11) Show SMILES Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cn3)c12)C1CC2(C1)CN(C2)C(=O)C=C Show InChI InChI=1S/C25H23N7O2/c1-2-20(33)31-13-25(14-31)10-16(11-25)32-24-21(23(26)28-15-29-24)22(30-32)19-9-8-18(12-27-19)34-17-6-4-3-5-7-17/h2-9,12,15-16H,1,10-11,13-14H2,(H2,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description An HTRF assay (Cisbio KinEASE-TK cat #62TKOPEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation of ...				US Patent US8940893 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J3P
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