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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM202133'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM202133
PNG
(US9233983, I-4)
Show SMILES CCN1CCN(Cc2ccc(nc2)-c2cc3c(ccnc3[nH]2)-c2cccc(N3CCOc4cc(ccc4C3=O)C3CC3)c2CO)CC1
Show InChI InChI=1S/C38H40N6O3/c1-2-42-14-16-43(17-15-42)23-25-6-11-33(40-22-25)34-21-31-29(12-13-39-37(31)41-34)28-4-3-5-35(32(28)24-45)44-18-19-47-36-20-27(26-7-8-26)9-10-30(36)38(44)46/h3-6,9-13,20-22,26,45H,2,7-8,14-19,23-24H2,1H3,(H,39,41)
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US Patent
n/an/a 2n/an/an/an/an/an/a



ADVINUS THERAPEUTICS LIMITED

US Patent


Assay Description
The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...

US Patent US9233983 (2016)


BindingDB Entry DOI: 10.7270/Q22J69PQ
More data for this
Ligand-Target Pair