Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM202218'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM202218 (US9233983, Q-1) Show SMILES OCc1c(cccc1-c1ccnc2[nH]c(cc12)-c1ccc(OCCN2CCOCC2)cn1)N1CCOc2cc(cc(F)c2C1=O)C1CC1 Show InChI InChI=1S/C37H36FN5O5/c38-30-18-24(23-4-5-23)19-34-35(30)37(45)43(13-17-48-34)33-3-1-2-26(29(33)22-44)27-8-9-39-36-28(27)20-32(41-36)31-7-6-25(21-40-31)47-16-12-42-10-14-46-15-11-42/h1-3,6-9,18-21,23,44H,4-5,10-17,22H2,(H,39,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
ADVINUS THERAPEUTICS LIMITED US Patent					Assay Description The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...				US Patent US9233983 (2016) BindingDB Entry DOI: 10.7270/Q22J69PQ
					More data for this Ligand-Target Pair