Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM206363'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM206363 (US9260415, 114) Show SMILES Cn1cc(cc(Nc2cccc(n2)N2CCC[C@@H](C2)NC(=O)C=C)c1=O)-c1ccnc(N2CCn3c4CC(C)(C)Cc4cc3C2=O)c1CO |r| Show InChI InChI=1S/C37H42N8O4/c1-5-33(47)39-25-8-7-13-43(21-25)32-10-6-9-31(41-32)40-28-16-24(20-42(4)35(28)48)26-11-12-38-34(27(26)22-46)45-15-14-44-29(36(45)49)17-23-18-37(2,3)19-30(23)44/h5-6,9-12,16-17,20,25,46H,1,7-8,13-15,18-19,21-22H2,2-4H3,(H,39,47)(H,40,41)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.888	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Genentech, Inc. US Patent					Assay Description A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...				US Patent US9260415 (2016) BindingDB Entry DOI: 10.7270/Q2WH2NT7
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