Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM225236'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM225236 (BTK inhibitor, 1) Show SMILES CNC(=O)C(Cc1c[nH]c2ncccc12)NC(=O)c1n[nH]c2cccc(CNc3ccc(O)cc3Cl)c12 |w:4.4| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	30
X-Chem Pharmaceuticals					Assay Description The BTK time-resolved FRET-based competitive binding assay and cell-based BTK assays have been previously described.[Xu et al., J.Pharmacol. Exp. The...				Chembiochem 18: 864-871 (2017) Article DOI: 10.1002/cbic.201600573 BindingDB Entry DOI: 10.7270/Q22J69Q5
					More data for this Ligand-Target Pair