Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM281754'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM281754 (US10023534, Example 13 | US10023534, Example 14) Show SMILES NC(=O)c1cc(F)c(-c2cccc3N(CCSc23)C(=O)C=C)c2c3ccccc3[nH]c12 |(1.6,6.16,;.26,5.39,;-1.07,6.16,;.26,3.85,;1.6,3.08,;1.6,1.54,;2.93,.77,;.26,.77,;.26,-.77,;-1.07,-1.54,;-1.07,-3.08,;.26,-3.85,;1.6,-3.08,;2.93,-3.85,;4.26,-3.08,;4.26,-1.54,;2.93,-.77,;1.6,-1.54,;2.93,-5.39,;1.6,-6.16,;4.26,-6.16,;5.6,-5.39,;-1.07,1.54,;-2.53,1.06,;-3.16,-.34,;-4.69,-.5,;-5.6,.74,;-4.97,2.15,;-3.44,2.31,;-2.53,3.56,;-1.07,3.08,)| Show InChI InChI=1S/C24H18FN3O2S/c1-2-19(29)28-10-11-31-23-14(7-5-9-18(23)28)20-16(25)12-15(24(26)30)22-21(20)13-6-3-4-8-17(13)27-22/h2-9,12,27H,1,10-11H2,(H2,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0730	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...				US Patent US10023534 (2018) BindingDB Entry DOI: 10.7270/Q2WW7KQR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM281754 (US10023534, Example 13 | US10023534, Example 14) Show SMILES NC(=O)c1cc(F)c(-c2cccc3N(CCSc23)C(=O)C=C)c2c3ccccc3[nH]c12 |(1.6,6.16,;.26,5.39,;-1.07,6.16,;.26,3.85,;1.6,3.08,;1.6,1.54,;2.93,.77,;.26,.77,;.26,-.77,;-1.07,-1.54,;-1.07,-3.08,;.26,-3.85,;1.6,-3.08,;2.93,-3.85,;4.26,-3.08,;4.26,-1.54,;2.93,-.77,;1.6,-1.54,;2.93,-5.39,;1.6,-6.16,;4.26,-6.16,;5.6,-5.39,;-1.07,1.54,;-2.53,1.06,;-3.16,-.34,;-4.69,-.5,;-5.6,.74,;-4.97,2.15,;-3.44,2.31,;-2.53,3.56,;-1.07,3.08,)| Show InChI InChI=1S/C24H18FN3O2S/c1-2-19(29)28-10-11-31-23-14(7-5-9-18(23)28)20-16(25)12-15(24(26)30)22-21(20)13-6-3-4-8-17(13)27-22/h2-9,12,27H,1,10-11H2,(H2,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.130	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...				US Patent US10023534 (2018) BindingDB Entry DOI: 10.7270/Q2WW7KQR
					More data for this Ligand-Target Pair