Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM340137'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM340137 (US10239883, Example 26 | US10934296, Example 26 | ...) Show SMILES CCCc1ccnc(NC(=O)c2ccc(cc2F)-c2nc([C@@H]3CCCCN3C(=O)C=C)n3ccnc(N)c23)c1 |r| Show InChI InChI=1S/C29H30FN7O2/c1-3-7-18-11-12-32-23(16-18)34-29(39)20-10-9-19(17-21(20)30)25-26-27(31)33-13-15-37(26)28(35-25)22-8-5-6-14-36(22)24(38)4-2/h4,9-13,15-17,22H,2-3,5-8,14H2,1H3,(H2,31,33)(H,32,34,39)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
Merck Sharp & Dohme B.V. US Patent					Assay Description Btk enzyme (His-Btk (Millipore catalog #14-552), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM D...				US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM340137 (US10239883, Example 26 | US10934296, Example 26 | ...) Show SMILES CCCc1ccnc(NC(=O)c2ccc(cc2F)-c2nc([C@@H]3CCCCN3C(=O)C=C)n3ccnc(N)c23)c1 |r| Show InChI InChI=1S/C29H30FN7O2/c1-3-7-18-11-12-32-23(16-18)34-29(39)20-10-9-19(17-21(20)30)25-26-27(31)33-13-15-37(26)28(35-25)22-8-5-6-14-36(22)24(38)4-2/h4,9-13,15-17,22H,2-3,5-8,14H2,1H3,(H2,31,33)(H,32,34,39)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
Merck Sharp & Dohme B.V. US Patent					Assay Description Btk enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Btk enzyme (H...				US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM340137 (US10239883, Example 26 | US10934296, Example 26 | ...) Show SMILES CCCc1ccnc(NC(=O)c2ccc(cc2F)-c2nc([C@@H]3CCCCN3C(=O)C=C)n3ccnc(N)c23)c1 |r| Show InChI InChI=1S/C29H30FN7O2/c1-3-7-18-11-12-32-23(16-18)34-29(39)20-10-9-19(17-21(20)30)25-26-27(31)33-13-15-37(26)28(35-25)22-8-5-6-14-36(22)24(38)4-2/h4,9-13,15-17,22H,2-3,5-8,14H2,1H3,(H2,31,33)(H,32,34,39)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Btk enzyme (His-Btk (Millipore catalog #14-552), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM D...				J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4
					More data for this Ligand-Target Pair