Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM351880'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM351880 (US9796716, Compound 125) Show SMILES Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nn(CC4(C)COC4)c4ncnc(N)c34)c2)s1 Show InChI InChI=1S/C27H25FN6O3S/c1-16-30-10-22(38-16)11-36-20-7-18(28)8-21(9-20)37-19-5-3-17(4-6-19)24-23-25(29)31-15-32-26(23)34(33-24)12-27(2)13-35-14-27/h3-10,15H,11-14H2,1-2H3,(H2,29,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PHARMASCIENCE, INC. US Patent					Assay Description Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length Bruton Aga...				US Patent US9796716 (2017) BindingDB Entry DOI: 10.7270/Q2MW2K8J
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