Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM374613'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM374613 (US10246457, Example 22) Show SMILES CC(C)(C)c1cc(F)c2c(cnn(-c3cccc(-c4cc(-c5ccccn5)c5[nH]nc(N)c5c4)c3CO)c2=O)c1 Show InChI InChI=1S/C31H27FN6O2/c1-31(2,3)19-11-18-15-35-38(30(40)27(18)24(32)14-19)26-9-6-7-20(23(26)16-39)17-12-21(25-8-4-5-10-34-25)28-22(13-17)29(33)37-36-28/h4-15,39H,16H2,1-3H3,(H3,33,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description Btk enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (lime-resolved fluorescence resonance energy transfer) assay...				J Med Chem 50: 1876-85 (2007) BindingDB Entry DOI: 10.7270/Q2833VB3
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM374613 (US10246457, Example 22) Show SMILES CC(C)(C)c1cc(F)c2c(cnn(-c3cccc(-c4cc(-c5ccccn5)c5[nH]nc(N)c5c4)c3CO)c2=O)c1 Show InChI InChI=1S/C31H27FN6O2/c1-31(2,3)19-11-18-15-35-38(30(40)27(18)24(32)14-19)26-9-6-7-20(23(26)16-39)17-12-21(25-8-4-5-10-34-25)28-22(13-17)29(33)37-36-28/h4-15,39H,16H2,1-3H3,(H3,33,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description Btk enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (lime-resolved fluorescence resonance energy transfer) assay...				J Med Chem 50: 1876-85 (2007) BindingDB Entry DOI: 10.7270/Q2833VB3
					More data for this Ligand-Target Pair