Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM377760'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM377760 (5-amino-1-(1-cyanopiperidin-3-yl)- 3-[4-(3-fluoro-...) Show SMILES Cc1c(F)cccc1Oc1ccc(cc1)-c1nn(C2CCCN(C2)C#N)c(N)c1C(N)=O Show InChI InChI=1S/C23H23FN6O2/c1-14-18(24)5-2-6-19(14)32-17-9-7-15(8-10-17)21-20(23(27)31)22(26)30(28-21)16-4-3-11-29(12-16)13-25/h2,5-10,16H,3-4,11-12,26H2,1H3,(H2,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description BTK: TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide p...				US Patent US10815213 (2020) BindingDB Entry DOI: 10.7270/Q2W95D87
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM377760 (5-amino-1-(1-cyanopiperidin-3-yl)- 3-[4-(3-fluoro-...) Show SMILES Cc1c(F)cccc1Oc1ccc(cc1)-c1nn(C2CCCN(C2)C#N)c(N)c1C(N)=O Show InChI InChI=1S/C23H23FN6O2/c1-14-18(24)5-2-6-19(14)32-17-9-7-15(8-10-17)21-20(23(27)31)22(26)30(28-21)16-4-3-11-29(12-16)13-25/h2,5-10,16H,3-4,11-12,26H2,1H3,(H2,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut Claudius Regaud					Assay Description TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide peptid...				J Med Chem 48: 287-91 (2005) BindingDB Entry DOI: 10.7270/Q2P271FD
					More data for this Ligand-Target Pair