Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM50063963'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM50063963 (CHEMBL3402585) Show SMILES OCc1c(cccc1-n1ccc2cc(cc(F)c2c1=O)C1CC1)-c1ncnc2[nH]c(cc12)C1=CCN(CC1)C(=O)N1CCOCC1 |t:38| Show InChI InChI=1S/C35H33FN6O4/c36-28-17-24(21-4-5-21)16-23-8-11-42(34(44)31(23)28)30-3-1-2-25(27(30)19-43)32-26-18-29(39-33(26)38-20-37-32)22-6-9-40(10-7-22)35(45)41-12-14-46-15-13-41/h1-3,6,8,11,16-18,20-21,43H,4-5,7,9-10,12-15,19H2,(H,37,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of BTK (unknown origin) after 1 hr by TR-FRET analysis				Bioorg Med Chem 23: 891-901 (2015) Article DOI: 10.1016/j.bmc.2014.10.043 BindingDB Entry DOI: 10.7270/Q2SN0BNZ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM50063963 (CHEMBL3402585) Show SMILES OCc1c(cccc1-n1ccc2cc(cc(F)c2c1=O)C1CC1)-c1ncnc2[nH]c(cc12)C1=CCN(CC1)C(=O)N1CCOCC1 |t:38| Show InChI InChI=1S/C35H33FN6O4/c36-28-17-24(21-4-5-21)16-23-8-11-42(34(44)31(23)28)30-3-1-2-25(27(30)19-43)32-26-18-29(39-33(26)38-20-37-32)22-6-9-40(10-7-22)35(45)41-12-14-46-15-13-41/h1-3,6,8,11,16-18,20-21,43H,4-5,7,9-10,12-15,19H2,(H,37,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of BTK in human Ramos cells after 20 mins by fluorescence assay				Bioorg Med Chem 23: 891-901 (2015) Article DOI: 10.1016/j.bmc.2014.10.043 BindingDB Entry DOI: 10.7270/Q2SN0BNZ
					More data for this Ligand-Target Pair