Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Fyn' and Ligand = 'BDBM340131'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM340131 (US10239883, Example 19 | US10934296, Example 19 | ...) Show SMILES Nc1nccn2c(nc(-c3ccc(cc3)C(=O)Nc3cc(ccn3)C(F)(F)F)c12)[C@@H]1CCCCN1S(=O)(=O)C=C |r| Show InChI InChI=1S/C26H24F3N7O3S/c1-2-40(38,39)36-13-4-3-5-19(36)24-34-21(22-23(30)32-12-14-35(22)24)16-6-8-17(9-7-16)25(37)33-20-15-18(10-11-31-20)26(27,28)29/h2,6-12,14-15,19H,1,3-5,13H2,(H2,30,32)(H,31,33,37)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Sharp & Dohme B.V. US Patent					Assay Description FynT enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.FynT enzyme ...				US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM340131 (US10239883, Example 19 | US10934296, Example 19 | ...) Show SMILES Nc1nccn2c(nc(-c3ccc(cc3)C(=O)Nc3cc(ccn3)C(F)(F)F)c12)[C@@H]1CCCCN1S(=O)(=O)C=C |r| Show InChI InChI=1S/C26H24F3N7O3S/c1-2-40(38,39)36-13-4-3-5-19(36)24-34-21(22-23(30)32-12-14-35(22)24)16-6-8-17(9-7-16)25(37)33-20-15-18(10-11-31-20)26(27,28)29/h2,6-12,14-15,19H,1,3-5,13H2,(H2,30,32)(H,31,33,37)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Sharp & Dohme B.V. US Patent					Assay Description FynT enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.FynT enzyme ...				US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM340131 (US10239883, Example 19 | US10934296, Example 19 | ...) Show SMILES Nc1nccn2c(nc(-c3ccc(cc3)C(=O)Nc3cc(ccn3)C(F)(F)F)c12)[C@@H]1CCCCN1S(=O)(=O)C=C |r| Show InChI InChI=1S/C26H24F3N7O3S/c1-2-40(38,39)36-13-4-3-5-19(36)24-34-21(22-23(30)32-12-14-35(22)24)16-6-8-17(9-7-16)25(37)33-20-15-18(10-11-31-20)26(27,28)29/h2,6-12,14-15,19H,1,3-5,13H2,(H2,30,32)(H,31,33,37)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description FynT enzyme (Biomol catalog #SE-287), is diluted to 0.5 μg/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2...				J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4
					More data for this Ligand-Target Pair