Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase HCK' and Ligand = 'BDBM142608'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase HCK (Homo sapiens (Human))	BDBM142608 (US8933228, 24) Show SMILES COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)n(C)c23)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C31H30N8O4/c1-31(2,3)24-16-25(39(37-24)18-10-13-26(42-5)33-17-18)35-29(40)34-21-11-12-22(20-9-7-6-8-19(20)21)43-23-14-15-32-28-27(23)38(4)30(41)36-28/h6-17H,1-5H3,(H,32,36,41)(H2,34,35,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...				US Patent US8933228 (2015) BindingDB Entry DOI: 10.7270/Q2RV0MDW
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