Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM159788'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM159788 (US10966980, Example 38 | US9035074, 38) Show SMILES CN([C@@H]1C[C@@H](C1)NS(=O)(=O)c1cnc(C)s1)c1ncnc2[nH]ccc12 |r,wD:2.1,4.6,(-5.46,.09,;-4.13,-.68,;-2.79,.09,;-2.4,1.58,;-.91,1.18,;-1.31,-.31,;.43,1.95,;1.76,1.18,;.99,-.15,;2.53,-.15,;3.09,1.95,;4.56,1.47,;5.46,2.72,;4.56,3.97,;5.33,5.3,;3.09,3.49,;-4.13,-2.22,;-5.46,-2.99,;-5.46,-4.53,;-4.13,-5.3,;-2.79,-4.53,;-1.33,-5.01,;-.43,-3.76,;-1.33,-2.51,;-2.79,-2.99,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Test article and assay controls were added to a 384-well plate. Reaction mixtures contained 20 mM HEPES, pH 7.4, 10 mM magnesium chloride, 0.01% bovi...				US Patent US10966980 (2021) BindingDB Entry DOI: 10.7270/Q29S1V59
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM159788 (US10966980, Example 38 | US9035074, 38) Show SMILES CN([C@@H]1C[C@@H](C1)NS(=O)(=O)c1cnc(C)s1)c1ncnc2[nH]ccc12 |r,wD:2.1,4.6,(-5.46,.09,;-4.13,-.68,;-2.79,.09,;-2.4,1.58,;-.91,1.18,;-1.31,-.31,;.43,1.95,;1.76,1.18,;.99,-.15,;2.53,-.15,;3.09,1.95,;4.56,1.47,;5.46,2.72,;4.56,3.97,;5.33,5.3,;3.09,3.49,;-4.13,-2.22,;-5.46,-2.99,;-5.46,-4.53,;-4.13,-5.3,;-2.79,-4.53,;-1.33,-5.01,;-.43,-3.76,;-1.33,-2.51,;-2.79,-2.99,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.4	25
Pfizer Inc. US Patent					Assay Description Test article and assay controls were added to a 384-well plate. Reaction mixtures contained 20 mM HEPES, pH 7.4, 10 mM magnesium chloride, 0.01% bovi...				US Patent US9035074 (2015) BindingDB Entry DOI: 10.7270/Q26H4G56
					More data for this Ligand-Target Pair