Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM150751'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM150751 (CPR005231 (6)) Show SMILES COc1cc(ccc1O)-c1ccc2ccc(-c3cccc(c3)C(=O)NCCN(C)C)n2n1 Show InChI InChI=1S/C25H26N4O3/c1-28(2)14-13-26-25(31)19-6-4-5-18(15-19)22-11-9-20-8-10-21(27-29(20)22)17-7-12-23(30)24(16-17)32-3/h4-12,15-16,30H,13-14H2,1-3H3,(H,26,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	7.5	25
University of Copenhagen					Assay Description The reaction was started by adding a mix of ATP and Peptide 38 to assay plates containing DAPK1. Prior to mixing, all reagents are diluted in assay b...				Chembiochem 16: 59-63 (2015) Article DOI: 10.1002/cbic.201402512 BindingDB Entry DOI: 10.7270/Q2XW4HHD
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