Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332934'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332934 (US10196390, Compound I-223) Show SMILES CN1CCNC(C)(C1=O)c1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2F)nc1 Show InChI InChI=1S/C24H22F2N6O2/c1-24(23(34)32(2)9-8-29-24)13-6-7-19(27-11-13)31-17-10-16(20-14(25)4-3-5-15(20)26)30-18-12-28-22(33)21(17)18/h3-7,10-11,29H,8-9,12H2,1-2H3,(H,28,33)(H,27,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
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