Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332974'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332974 (US10196390, Compound I-263) Show SMILES C[C@@H]1COC[C@@H](C)N1c1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2F)nc1 |r| Show InChI InChI=1S/C24H23F2N5O2/c1-13-11-33-12-14(2)31(13)15-6-7-21(27-9-15)30-19-8-18(22-16(25)4-3-5-17(22)26)29-20-10-28-24(32)23(19)20/h3-9,13-14H,10-12H2,1-2H3,(H,28,32)(H,27,29,30)/t13-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
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