Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332989'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332989 (US10196390, Compound I-278) Show SMILES CC(C)(C)Nc1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2F)nc1 Show InChI InChI=1S/C22H21F2N5O/c1-22(2,3)29-12-7-8-18(25-10-12)28-16-9-15(19-13(23)5-4-6-14(19)24)27-17-11-26-21(30)20(16)17/h4-10,29H,11H2,1-3H3,(H,26,30)(H,25,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
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