Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50208588'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50208588 (CHEMBL3884240) Show SMILES NS(=O)(=O)c1cccc(Nc2ccnc(Nc3ccc(cc3)N3CCOCC3)n2)c1 Show InChI InChI=1S/C20H22N6O3S/c21-30(27,28)18-3-1-2-16(14-18)23-19-8-9-22-20(25-19)24-15-4-6-17(7-5-15)26-10-12-29-13-11-26/h1-9,14H,10-13H2,(H2,21,27,28)(H2,22,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
Kasetsart University Curated by ChEMBL					Assay Description Inhibition of human JAK2 using poly (Glu:Tyr) as substrate				Eur J Med Chem 124: 896-905 (2016) Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q
					More data for this Ligand-Target Pair