Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50208589'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50208589 (CHEMBL3884848) Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(C)c3)n2)cc1C Show InChI InChI=1S/C23H28N6/c1-17-5-4-6-19(15-17)25-22-9-10-24-23(27-22)26-20-7-8-21(18(2)16-20)29-13-11-28(3)12-14-29/h4-10,15-16H,11-14H2,1-3H3,(H2,24,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Kasetsart University Curated by ChEMBL					Assay Description Inhibition of human JAK2 using poly (Glu:Tyr) as substrate				Eur J Med Chem 124: 896-905 (2016) Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q
					More data for this Ligand-Target Pair