Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50303067'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50303067 ((R)-3-(6-(1-phenylethylamino)pyrimidin-4-yl)pyrazo...) Show SMILES C[C@@H](Nc1cc(ncn1)-c1c(N)nn2cccnc12)c1ccccc1 |r| Show InChI InChI=1S/C18H17N7/c1-12(13-6-3-2-4-7-13)23-15-10-14(21-11-22-15)16-17(19)24-25-9-5-8-20-18(16)25/h2-12H,1H3,(H2,19,24)(H,21,22,23)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of JAK2 by radiometric assay				Bioorg Med Chem Lett 19: 6529-33 (2009) Article DOI: 10.1016/j.bmcl.2009.10.053 BindingDB Entry DOI: 10.7270/Q2SJ1MKQ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50303067 ((R)-3-(6-(1-phenylethylamino)pyrimidin-4-yl)pyrazo...) Show SMILES C[C@@H](Nc1cc(ncn1)-c1c(N)nn2cccnc12)c1ccccc1 |r| Show InChI InChI=1S/C18H17N7/c1-12(13-6-3-2-4-7-13)23-15-10-14(21-11-22-15)16-17(19)24-25-9-5-8-20-18(16)25/h2-12H,1H3,(H2,19,24)(H,21,22,23)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of JAK2-mediated STAT5 phosphorylation in GMCSF-stimulated human TF1 cells				Bioorg Med Chem Lett 19: 6529-33 (2009) Article DOI: 10.1016/j.bmcl.2009.10.053 BindingDB Entry DOI: 10.7270/Q2SJ1MKQ
					More data for this Ligand-Target Pair