Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50305175'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50305175 (9-(2,3,6-trifluorophenyl)-8,12,14-triazatetracyclo...) Show SMILES Fc1ccc(F)c(C2Nc3ccccc3-c3ccnc4[nH]cc2c34)c1F Show InChI InChI=1S/C20H12F3N3/c21-13-5-6-14(22)18(23)17(13)19-12-9-25-20-16(12)11(7-8-24-20)10-3-1-2-4-15(10)26-19/h1-9,19,26H,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of JAK2 by radiometric assay				Bioorg Med Chem Lett 20: 153-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.021 BindingDB Entry DOI: 10.7270/Q2PN95RQ
					More data for this Ligand-Target Pair