Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50305193'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50305193 (CHEMBL589387 | Methyl 9-(3-fluoro-4-hydroxyphenyl)...) Show SMILES COC(=O)C1(Nc2ccccc2-c2ccnc3[nH]cc1c23)c1ccc(O)c(F)c1 Show InChI InChI=1S/C22H16FN3O3/c1-29-21(28)22(12-6-7-18(27)16(23)10-12)15-11-25-20-19(15)14(8-9-24-20)13-4-2-3-5-17(13)26-22/h2-11,26-27H,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of JAK2 by radiometric assay				Bioorg Med Chem Lett 20: 153-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.021 BindingDB Entry DOI: 10.7270/Q2PN95RQ
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