Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50337339'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50337339 (1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...) Show SMILES Cc1cc(Nc2nc(nn3cccc23)N2CCN(CC2)C(=O)CCc2ccccc2)[nH]n1 Show InChI InChI=1S/C23H26N8O/c1-17-16-20(27-26-17)24-22-19-8-5-11-31(19)28-23(25-22)30-14-12-29(13-15-30)21(32)10-9-18-6-3-2-4-7-18/h2-8,11,16H,9-10,12-15H2,1H3,(H2,24,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of JAK2 after 60 mins				Bioorg Med Chem Lett 21: 1425-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.022 BindingDB Entry DOI: 10.7270/Q2MG7PRT
					More data for this Ligand-Target Pair